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We are looking for individuals from diverse backgrounds to join our team.
We are looking for individuals from diverse backgrounds to join our team.
LABORATORY FOR HUMAN EMBRYOMIMETICS
The first weeks of embryo development are perhaps the most remarkable example of biological organization. During this time, the specialization of cells begins and the embryonic tissues transform from a uniform ball of cells into highly organized layers of organ tissues. We call this process organogenesis.
A great feat of organogenesis is that it always directs cells into the right place at the right time. A kidney must look and function like a kidney and never like a liver or a brain. Carefully positioned signaling centers in the embryo create gradients of chemical signals that ensure the precise and ordered patterning of organs. Where a cell is located in the signaling gradient will determine its unique fate within an organ anywhere along the body axes.
Recreating human organs in a lab is one of the most coveted scientific goals of our time. Learning lessons from early development, we are now able to harness the developmental potential of pluripotent stem cells and mimic in vitro the chemical signals as they would happen in the embryo. We can recreate an approximative embryo in a dish from nothing but stem cells and even generate tiny versions of human organs that we call organoids.
We are an interdisciplinary group of researchers whose mission is to advance the knowledge of human embryonic development and to contribute to its application in reproductive and regenerative medicine. We bridge the gap between biomolecular engineering, developmental biology, and biophysics, and our interests range from developing new organoid tech to elucidating the fundamental biology behind embryonic patterning and organ development, in health and disease. If you'd like to collaborate with us or join our lab, get in touch.
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