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We are looking for individuals from diverse backgrounds to join our team.
We are looking for individuals from diverse backgrounds to join our team.
LABORATORY FOR EMBRYOMIMETICS
The development of organs is perhaps the most remarkable feat of biological organization. During embryonic development, the specialization of cells begins and the embryonic tissues transform from a uniform ball of cells into highly organized layers of organ tissues. We call this process organogenesis.
A great feat of organogenesis is that it always directs cells into the right place at the right time. A kidney must look and function like a kidney and never like a liver or a brain. Carefully positioned signaling centers create gradients of chemical signals that ensure the precise and ordered patterning of organs. Where a cell is located in the signaling gradient will determine its unique fate within an organ anywhere along the body axes.
Recreating and rejuvenating human organs in a lab is one of the most coveted scientific goals of contemporary biology. Learning lessons from early development, we are now able to harness the developmental potential of pluripotent stem cells and mimic in vitro the chemical signals that would shape developing organs. We can leverage stem cells to recreate tiny versions of human organs that we call organoids.
We are an interdisciplinary group of researchers whose mission is to advance our knowledge of organogenesis and to engineer novel solutions for reproduction and tissue regeneration. We bridge the gap between biomolecular engineering and developmental biology, and our interests range from developing new organoid tech to elucidating the fundamental biology behind embryonic patterning and organ development, in health and disease. If you'd like to collaborate with us or join our lab, get in touch.
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